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What is drug-free IVF?

In vitro fertilisation without drugs, unlike conventional IVF treatment, ova are collected and matured in a laboratory environment before maturation. The reason for this is that patients do not want to be harmed by the medication used to mature the ova.In the 1990s, drug-free IVF treatment was preferred in the laboratory setting. In particular, it was implemented to be used in patients with polycystic ovary syndrome, i.e. overreaction to medication. Patients with polycystic ovary syndrome are very sensitive to the effect of the drug called gonadotropin, which stimulates the ovaries, and some complications, including hospitalisation, may occur.

Who can have the medication-free IVF method performed?

This treatment method can be used for women with few ovules and women with polycystic ovary syndrome. It is preferred when it is not possible to collect very many ova with a needle, it ensures that no drugs are used and it costs less. It ensures that no complications occur in patients with polycystic ovary syndrome.

What are the advantages of medication-free IVF treatment?

  • It is less costly as no ovulation injections are used.
  • The patient has no side effects from ovulation-promoting treatments.
  • The patient is treated with few checks and ultrasound.
Embryos obtained in drug-free in vitro fertilisation can be genetically diagnosed as in the classical IVF method. In addition, a blastocyst transfer can be performed and even embryos can be frozen for later use if desired.Despite its advantages, the reason why medication-free in vitro fertilisation is not widely used is that it does not achieve the desired success rate.
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